Hydrogel-Based Artificial Blood as a Lubricant in Bio-Tribological Model System Testing

Authors

DOI:

https://doi.org/10.31265/atnrs.769

Abstract

Understanding the tribological behavior of blood-lubricated interfaces is considered relevant  for the design of heart pumps, heart valves or for the understanding of the blood flow in very  narrow blood vessels. Tribological studies with real biological materials are challenging, e.g.,  due to their limited stability or potential risk of infections. To overcome these challenges,  artificial materials are used in this study to mimic real blood and the biological interfaces. As
for the lubricant, a hydrogel-based artificial blood with a glycerol-water solution, as a continuous phase, is used. Various compositions of artificial blood are investigated and  compared with real plasma as well as platelet-rich plasma as lubricants. Soft biological  interfaces are represented by a glass-ball-on-three-elastomeric pins setup.  Results from tribological model system measurements on the different lubricants are shown in  the form of Stribeck curves and possible lubricating mechanisms are discussed. Results from  complementary shear rheological measurements of the blood fluids are shown and discussed.

Author Biographies

Florian Pape

Institute of Machine Elements and Engineering
Design Researcher, Team Leader
Leibniz University

Gesine Hentschel

Institute of Multiphase Processes
Leibniz University
Hannover

Belal Nassef

Institute of Machine Design and Tribology
Leibniz University

Florian Rummel

NETZSCH-Gerätebau GmbH

Sabrina Küspert

NETZSCH-Gerätebau GmbH

Ligia de Souza

NETZSCH-Gerätebau GmbH

Christina Winkler

Institute of Multiphase Processes
Leibniz University
Hannover

Birgit Glasmacher

Institute of Multiphase Processes
Leibniz University
Hannover

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Published

2024-05-21